Working Party Guidance on the control of multi-resistant Acinetobacter outbreaks

Publication date: Available online 29 May 2019Source: Journal of Hospital InfectionAuthor(s): Barry Cookson
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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After publication of the original article [1], we were notified that an author ’s name has been incorrectly spelled. Sedzro Divine Mensal should be replaced with Sedzro Divine Mensah.
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correction Source Type: research
Abstract Nosocomial infections have become alarming with the increase of multidrug-resistant bacterial strains of Acinetobacter baumannii. Being the causative agent in ~80% of the cases, these pathogenic gram-negative species could be deadly for hospitalized patients, especially in intensive care units utilizing ventilators, urinary catheters, and nasogastric tubes. Primarily infecting an immuno-compromised system, they are resistant to most antibiotics and are the root cause of various types of opportunistic infections including but not limited to septicemia, endocarditis, meningitis, pneumonia, skin, and wound s...
Source: Genomics Proteomics ... - Category: Genetics & Stem Cells Authors: Tags: Front Cell Infect Microbiol Source Type: research
The typing of epidemic bacterial pathogens in hospitals relies on DNA-based, expensive, and time-consuming techniques, that are often limited to retrospective studies. However, the quick identification of epidemic pathogens in the routine of the microbiology laboratories would expedite infection control procedures that limit the contamination of new patients. IR Biotyper (Bruker Daltonics GmbH) is a new typing machine based on Fourier-transform infrared (FTIR) spectroscopy, aiming at typing the micro-organisms within 3 hours based on the difference in polysaccharides spectra. In this work, we evaluated the ability of the F...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Acinetobacter baumannii has emerged as an important nosocomial pathogen in recent years, with infectious outbreaks caused by multidrug-resistant strains increasing worldwide. Thus, new antibacterial treatments for multidrug-resistant A. baumannii strains are needed. In this work, a series of 5-hydrazinylethylidenepyrimidines were synthesized and in vitro evaluated against two multidrug-resistant A. baumannii strains (AcB 13/10 and AcB 73/10). Minimum inhibitory concentration results demonstrated that generally the compounds in study presented values in a low micromolar range. In the determination of in vi...
Source: European Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharm Sci Source Type: research
Nosocomial infections have become alarming with the increase of multidrug resistant bacterial strains of Acinetobacter baumannii. Being the causative agent in approximately 80% of the cases, these pathogenic gram-negative species could be deadly for hospitalized patients, especially in intensive care units utilizing ventilators, urinary catheters and nasogastric tubes. Primarily infecting an immuno-compromised system, they are resistant to most antibiotics and are the root cause of various types of opportunistic infections including but not limited to septicemia, endocarditis, meningitis, pneumonia, skin and wound sepsis a...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
ConclusionThe ability to persist for long periods on different surfaces, mimicking those usually found in hospitals, along with A. baumannii's capacity to survive after a disinfection process may account for the recurrent outbreaks in intensive care units.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
To investigate the carbapenem resistance mechanisms and clonal relationship of carbapenem-resistant Acinetobacter baumannii (CRAB) strains isolated in the intensive care unit (ICU) of the First Affiliated Hospita...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
ConclusionThe HAI surveillance system successfully detected and facilitated the control of theA.baumannii outbreak. Whole-genome sequencing was found to be a useful method for differentiation of phenotypically identicalA.baumannii strains from the intrahospital outbreak. Only multi-modal infection control program, including closure, temporary relocation, and renovation of the ward, restricted the outbreak.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Julija Armalytė1, Jūratė Skerniškytė1, Elena Bakienė1, Renatas Krasauskas1, Rita Šiugždinienė2, Violeta Kareivienė2, Sigita Kerzienė2, Irena Klimienė2, Edita Sužiedėlienė1 and Modestas Ružauskas2* 1Life Sciences Center, Institute of Biosciences, Vilnius University, Vilnius, Lithuania 2Institute of Microbiology and Virology, Lithuanian University of Health Sciences, Kaunas, Lithuania Soil is one of the biggest reservoirs of microbial diversity, yet the processes that define the community dynamics are not fully understood. Apart from soil management being vital for agricultural purposes...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
ConclusionThe ability to persist for long periods on different surfaces mimicking those usual found in hospitals along with the A. baumannii capacity to survive after disinfection process could be accountable for the recurrent outbreaks in intensive care units (ICUs).
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
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