Telomerase insufficiency induced telomere erosion accumulation in successive generations in dyskeratosis congenita family

ConclusionsOur study identified three clinical pathologicTERT mutations and implied that telomere erosion might be accumulated through successive generations, contributing to the severity of DC in the younger generation.

Source: Molecular Genetics & Genomic Medicine - May 21, 2019 Category: Genetics & Stem Cells Authors: Caixia He, Shuang Jing, Congling Dai, Chaofeng Tu, Zhenhua Tan, Juan Du, Guang ‐Xiu Lu, Ge Lin, Sicong Zeng Tags: ORIGINAL ARTICLE Source Type: research