Objective and Subjective Effects of a Prototype Nasal Dilator Strip on Sleep in Subjects with Chronic Nocturnal Nasal Congestion

AbstractIntroductionThis exploratory study characterized the performance of a nasal dilator strip with improved spring forces in lowering nasal resistance during sleep and reducing sleep-disordered breathing in subjects with difficulty sleeping due to chronic nocturnal nasal congestion.MethodsSubjects applied the strip at bedtime for 28  days (active phase;n = 70). Objective assessments included snoring variables, breathing route during sleep, and polysomnography measures compared with baseline. Nasal breathing, congestion, and sleep were measured subjectively using rating scales and questionnaires. During a crossover nasal resistance phase (n = 55), nasal resistance was measured using posterior rhinomanometry with the strip applied on one of two nights.ResultsIn the active phase, breathing and sleep were perceived to improve, with less daytime sleepiness (P  
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research

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ConclusionsOur findings suggest that snoring changes autonomic nervous system (ANS) activity in adolescents; the changes are more dramatic in males and those with insufficient sleep.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
Conclusion: :OSA is not uncommon in asthma patients. Careful assessment of sleep related symptoms and demographic parameters of asthma patients are essential to suspect diagnosis of OSA. Additional factors like smoking, obesity, GERD and allergic rhinitis are important contributing factor for higher risk of OSA among asthma patients. Early diagnosis of OSA in asthma patients by polysomnography may have a clinical benefit in the management of both diseases. PMID: 31321930 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusions:Intranasal steroids and montelukast did not decrease AHI; however, total sleep time and percent of stage R sleep significantly increased. Self-reported improvement could be explained by observed changes in sleep parameters. Larger prospective studies could help elucidate the effects of medical therapy on adult patients with OSA.Clinical Trial Registration:Registry: ClinicalTrials.gov; Title: Montelukast and Nasa ICS for Treatment of Mild Obstructive Sleep Apnea in Adults; Identifier: NCT01089647; URL:https://clinicaltrials.gov/ct2/show/record/NCT01089647Citation:Smith DF, Sarber KM, Spiceland CP, Ishman SL, Aug...
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
CONCLUSION: Modified barbed pharyngoplasty is a safe and feasible method, and eliminates the need for surgical resection of the redundant soft tissues around the uvula while lifting up the uvula base. PMID: 31288877 [PubMed - as supplied by publisher]
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
Abstract BACKGROUND: We developed and implemented a perioperative guideline for obstructive sleep apnea (OSA), comprising a preoperative screening tool (BOSTN) and clinical management pathways. OSA was suspected with 2 or more of the following: body mass index ≥30 kg/m, observed apnea, loud snoring, daytime tiredness, and neck circumference ≥16.5 inches in women or ≥ 17.5 inches in men. The primary objective of this study was to assess the association between high BOSTN scores and the requirement of invasive mechanical ventilation after surgery. METHODS: In this hospital registry study, 169,662 nonca...
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
Conclusion: Approximately one-third of the patients may be at the risk of SDB 1 week after primary palatoplasty. Patients with history of laryngomalacia or those who required oxygen support for prolonged time after primary palatoplasty should be cared for significantly high risk of postoperative SDB.
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Clinical Studies Source Type: research
A 37-year-old man presented to the primary care clinic with fatigue, subjective muscle weakness, erectile dysfunction, and decreased libido of several months' duration. These symptoms had progressively worsened over several months. He also reported poor morning erections, decreased motivation, loss of interest in activities he previously found enjoyable, depression, anxiety, sleep disturbance, and snoring. He reported no weight changes, headaches, or vision changes. His medical history was notable for generalized anxiety, gastroesophageal reflux disease, and long-standing obesity.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Residents' clinic Source Type: research
Abstract CASE PRESENTATION: A 15-year-old girl was referred to us for sleep difficulties and restless sleep. The parent stated that she was always a poor sleeper, having difficulty falling asleep and frequent nocturnal awakenings since she was a very young child, but in the past 6 months the symptoms had worsened. She slept in her own room and in her own bed. Her bedtime was 10:30 pm, staying in bed anywhere from 2 to 5 h before she could fall asleep. During this time, she felt discomfort in her legs with the urge to move her legs and relief after movement. This sensation was worse at night or when sitti...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
Researchers at the University of Washington have used machine learning to teach an AI system to identify when someone is having a cardiac arrest. The system learned to identify agonal breathing, which occurs when someone gasps for breath during cardi...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Emergency Medicine Informatics Net News cardiac arrest heart attacks Source Type: blogs
Emerging Knowledge for Clinical Practice Podium Presentations focusing on the Research Agenda Priority of Pediatric Research: Professional Role&Health Promotion and Disease Prevention, Presented at NAPNAP's 40th National Conference on Pediatric Health Care, March 8, 2019, New Orleans, LA.
Source: Journal of Pediatric Health Care - Category: Pediatrics Authors: Source Type: research
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