A Machine Learning Algorithm to Estimate Sarcopenia on Abdominal CT

ConclusionThis system fully-automatically and accurately segments multiple muscle groups at all lumbar spine levels on abdominal CT for detection of sarcopenia.
Source: Academic Radiology - Category: Radiology Source Type: research

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Abstract OBJECTIVE: To investigate a fully-automated abdominal CT-based muscle tool in a large adult screening population. METHODS: A fully-automated validated muscle segmentation algorithm was applied to 9310 non-contrast CT scans, including a primary screening cohort of 8037 consecutive asymptomatic adults (mean age, 57.1±7.8 years; 3555M/4482F). Sequential follow-up scans were available in a subset of 1171 individuals (mean interval, 5.1 years). Muscle tissue cross-sectional area and attenuation (HU) at the L3 level were assessed, including change over time. RESULTS: Mean values were significan...
Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
437Objectives: Brown Adipose Tissue (BAT) is present in a significant number of adult humans and can be activated by exposure to cold. BAT is a metabolically-active fat that burns free fatty acids to produce heat. The aim of this study was to assess metabolic changes associated with the activation of BAT. Methods: Healthy adults with a body mass index (BMI) less than 25.0 and who were under the age of 35 were enrolled in this prospective study. Volunteers fasted for at least 6 hours prior to the study visit. In order to activate BAT, volunteers were cooled using a water perfusion suit for 60 minutes prior to administration...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: NETs, BAT and All That Source Type: research
Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease Tracy R. Melzer1,2,3†, Megan R. Stark1,2†, Ross J. Keenan1,4, Daniel J. Myall1, Michael R. MacAskill1,2, Toni L. Pitcher1,2,3, Leslie Livingston1,2, Sophie Grenfell1, Kyla-Louise Horne1,2, Bob N. Young1, Maddie J. Pascoe1, Mustafa M. Almuqbel1,2,4, Jian Wang5, Steven H. Marsh6, David H. Miller1,2,7, John C. Dalrymple-Alford1,2,3,8 and Tim J. Anderson1,2,3,9* 1New Zealand Brain Research Institute, Christchurch, New Zealand 2Department of Medicine, University of Otago, Christchurch, New Zealand 3Brain Rese...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Cheng Luo1†, Xiqing Bian1†, Qian Zhang2, Zhenyan Xia1, Bowen Liu1, Qi Chen1, Chienchih Ke3,4, Jian-Lin Wu1* and Yonghua Zhao5* 1State Key Laboratory of Quality Research in Chinese Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau, China 2Department of Biotherapy, Shenzhen Luohu People’s Hospital, Shenzhen, China 3Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan 4Biomedical Imaging Research Center, National Yang-Ming University, Taipei, Taiwan 5State Key Laboratory of Quality Research in Chinese Medi...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Grand Total EEG Score Can Differentiate Parkinson's Disease From Parkinson-Related Disorders Ela Austria Barcelon1,2*, Takahiko Mukaino1, Jun Yokoyama1, Taira Uehara2, Katsuya Ogata2, Jun-ichi Kira1 and Shozo Tobimatsu2 1Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan2Department of Clinical Neurophysiology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Background: Semi-quantitative electroencephalogram (EEG) analysis is easy to perform and has been used to differentiate dementias, as well ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion and Future Perspectives Although interesting data have come from pharmacogenetics, neuroimaging and the interaction of both fields of study, few converging findings are available that describe the antipsychotic treatment response and resistance mechanisms in schizophrenia (DeLisi and Fleischhacker, 2016). Based on the available evidence, the results from both neuroimaging and pharmacogenetic/pharmacogenomic studies point to an overlap in the neurobiological vulnerability risk factors influencing the antipsychotic drug response in schizophrenia and the risk factors underlying schizophrenia itself. Currently for ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONPancreatitis should be considered in the differential diagnosis of abdominal pain post-colonoscopy after the more common explanations are excluded.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionA lung CT scan is able to reflect the early-stage lung injuries of rabbits with different levels of severe inhalation injury.
Source: Burns - Category: Dermatology Source Type: research
Objectives: To identify and describe the thin-section computed tomographic findings of inhalation injury in burned patients, to determine which findings contribute to subsequent pulmonary complications.Methods: Thin-section CT scans of 90 burned patients with smoke inhalation injury were retrospectively reviewed. Individual CT features were assessed and recorded by one observer. Lung lesion patterns seen at CT, bronchoscopic findings, laboratory data and clinical consequences were analyzed.Results: 43 (47.8%) were found to have abnormal CT findings that were compatible with inhalation injury; 28 (65.1%), to have peribronch...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Acute Critical Care Source Type: research
Publication date: June 2018Source: Burns, Volume 44, Issue 4Author(s): Yang Chang, Dong-hai Zhang, Quan Hu, Ling-ying Liu, Yong-hui Yu, Jia-ke ChaiAbstractBackgroundBurn–blast combined injury is a kind of injury caused by heat and blast at the same time. The lung injury after burn–blast combined injuries is of primary importance, and investigation of lung injury is needed in the clinical care of patients. Computed tomography (CT) is one of the standard tools used to observe the anatomical basis and pathophysiology of acute lung injury.MethodsWe applied a method of fast 3D (three-dimensional) reconstruction to c...
Source: Burns - Category: Dermatology Source Type: research
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