Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension

This study reinforces our understanding of the interplay between physiological factors and ophthalmic formulation physicochemical properties and their impact onin vivo ocular drug PK performance in rabbits.
Source: The AAPS Journal - Category: Drugs & Pharmacology Source Type: research