Identifying Source Proteins for MHC Class I-Presented Peptides
Identification of antigenic peptides recognized by cytolytic T lymphocytes (CTL) is a prerequisite for the development of targeted cancer immunotherapy approaches. This chapter provides a global approach for the identification of peptides recognized by CTL. It implies the identification of the HLA molecule presenting the peptide as well as the design and screening of a cDNA library derived from the tumor cells.
Source: Springer protocols feed by Immunology - Category: Allergy & Immunology Source Type: news
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