Paraneoplastic nodular regenerative hyperplasia of the liver associated with placental site trophoblastic tumor

Publication date: Available online 18 May 2019Source: Gynecologic Oncology ReportsAuthor(s): Kathryn Dumas, MaryAnn Wilbur, Jessica Dillon, William Cliby, Carrie Langstraat, Amanda N. Fader, Deyin Xing, Rebecca L. Stone
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research

Related Links:

Urticarial vasculitis is a rare diagnosis defined by its distinct clinical and pathologic entities. The majority of cases are idiopathic; however, it has been linked to various etiologies including autoimmune, viral, paraneoplastic as well as pharmacotherapy. A 42-year-old Jamaican woman G1PO with sickle cell trait was admitted for persistent fevers and rigors for 2 weeks. This was associated with progressive burning, erythematous, raised plaques and patches involving the chest and trunk. While hospitalized she continued to spike fevers up to 103 °F despite being on broad spectrum antibiotics and acetaminophen.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
We present the case of a patient with paraneoplastic acral vascular syndrome as an initial manifestation of lung cancer.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Paraneoplastic icthyosis (PI) is an acquired icthyosis presenting as cutaneous xerosis and scaling of different severities associated with an underlying systemic disease that may be neoplastic or nonneoplastic in origin. A 59-year-old female with a history of diabetes and hypertension, presented to our dermatology department with a 1-month history of disseminated scaling, accompanied by pruritus, xerosis, asthenia, and nonintentional weight-loss of approximately 5 kg. Further physical examination revealed erythematous plaques in the sub-mammarian, axillary and inguinal folds consistent with intertrigo.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Introduction: Necrolytic migratory erythema (NME) may correspond to a paraneoplastic syndrome. It usually occurs in patients with glucagonoma, an alpha cell pancreatic tumor. When associated with weight loss, angular stomatitis, glossitis, diabetes mellitus, anemia and neuropsychiatric disorders defines the glucagonoma syndrome. NME lesions present as erythematous maculopapules with blisters and ulceration, occurring mostly on perineum, lower abdomen, extremities and face.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
We present the case of a 58-year-old Caucasian woman with a 7-year history of chronic pruritic, erythematous, annular, scaly plaques of the upper and lower extremities refractory to topical steroids.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Introduction: Sweet syndrome (SS), also known as febrile neutrophilic dermatosis is a clinical condition characterized by painful, tender, erythematous plaques and nodules, fever, neutrophilia and a diffuse mature neutrophilic infiltrate in the dermis. It can present as an idiopathic entity, associated with systemic drugs or as a paraneoplastic debut of underlying malignancy.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Abstract Immune-mediated inflammation of the brain has been recognized for more than 50 years, although the initial descriptions were mainly thought to be secondary to an underlying neoplasm. Some of these paraneoplastic encephalitides express serum antibodies, but these were not thought to be pathogenic but instead have a T-cell-mediated pathophysiology. Over the last two decades, several pathogenic antibodies against neuronal surface antigens have been described in autoimmune encephalitis, which are amenable to immunotherapy. Several of these antibodies are directed against glutamate receptors (GluRs). NMDA...
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
POEMS syndrome is a rare paraneoplastic condition associated to an underlying plasmacellular dyscrasia. POEMS is the acronym referring to the main features of this syndrome: polyradicoloneuropathy, organomegaly, endocrinopathy, monoclonal plasma-cell disorder and skin changes [1 –3]. The use of alkylating agents and autologous peripheral blood stem cell transplantation (aPBSCT) seems to be the best strategy in eligible patients [4–8]. At present aPBSCT should be considered first-line therapy in young patients with POEMS syndrome, eligible for High-Dose Melphalan (HD-Mel ), in absence of organ dysfunction.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: Brief article Source Type: research
We report 2 patients with acute occlusion of middle cerebral artery successfully treated by mechanical thrombectomy performed via transbrachial access. Both patients had floating aortic arch thrombi precluding safe transfemoral access due to risk of further iatrogenic embolization. Moreover both patients were diagnosed with hypercoagulopathy secondary to lung malignancy (paraneoplastic etiology, Trousseau's syndrome) as the cause of both aortic thrombi and acute ischemic stroke. Mechanical thrombectomy in the setting of a floating aortic thrombus has been mentioned only once as part of general management of floating aortic...
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
This article reviews the recent advances on the antibody detection, neuroimaging and treatment of autoimmune encephalitis. AbstractNon ‐infectious encephalitis has been a recognized entity for many years; however, its pathophysiology was not fully understood. Patients (usually women) presented with acute behavioral changes and were admitted to mental hospitals, without a correct diagnosis. With the new advances on antibody detect ion, the non‐infectious encephalitis panorama has been changing. Immune‐mediated diseases of the central nervous system encompass a variety of disorders, including the classic paraneoplastic...
Source: Clinical and Experimental Neuroimmunology - Category: Neurology Authors: Tags: Review Article Source Type: research
More News: Cancer & Oncology | Liver | OBGYN | Paraneoplastic Syndrome | Urology & Nephrology