What is the Optimal Cycle Regimen for Frozen- Thawed Embryo Transfer Cycles

Conditions:   Infertility;   Female Infertility;   Pregnancy Early Intervention:   Sponsor:   IVI Middle East Fertility Clinic Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Publication date: Available online 18 October 2019Source: Meta GeneAuthor(s): Mai Shaker, Taghreed Shalabi, Khaled R. Gaber, Khalda AmrAbstractBackgroundLeptin is an important hormone during implantation processes and plays a pivotal role in regulating the development of placenta and endo-metrial receptivity. miRNAs are associated with endometrial diseases, preeclampsia, neural tube defects and infertility, providing their potential role in the function of normal reproductive system. The aim of this study was to investigate the role of miRNA-27a and leptin polymorphisms in the development of idiopathic recurrent pregnancy ...
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 18 October 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Eleanor P Thong, Ethel Codner, Joop S E Laven, Helena TeedeSummaryReproductive dysfunction is a common but little studied complication of diabetes. The spectrum of reproductive health problems in diabetes is broad, and encompasses delayed puberty and menarche, menstrual cycle abnormalities, subfertility, adverse pregnancy outcomes, and potentially early menopause. Depending on the age at diagnosis of diabetes, reproductive problems can manifest early on in puberty, emerge later when fertility is desired, or occur duri...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
AbstractPurposeEmpirical treatment options for unexplained infertility treatment include controlled ovarian stimulation (COS) with clomiphene citrate, letrozole or gonadotropins followed by intrauterine insemination (IUI). Achieving consistent multifollicular development with letrozole generally requires addition of gonadotropins. However, the cost and discomfort of injections remains a drawback of this regimen. Therefore, there is a need for evolving newer cost-effective regimens for COS/IUI using orally administered drugs like letrozole.MethodsSixty couples with unexplained infertility (on standard infertility investigat...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
AbstractPurposeThe purpose of the study was to assess the fertilization rate and embryo development in sibling human oocytes after split insemination in patients with and without isolated teratozoospermia.MethodsA prospective cohort study at a university affiliated reproduction center was performed. Hundred and three patients during the time periods 01-2013 to 12-2015 had split insemination ordered for their first IVF cycle. The primary outcome measured was fertilization rate. Secondary outcomes were the number and quality of embryos.ResultsMature oocytes at the time of collection were assigned as follows: 558 to IVF and 5...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Danish-developed ExSeed uses the same software found in fertility clinics. It analyses the most common causes of male infertility - low sperm count and low motility.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Discussion: The incidence of rhabdomyosarcoma arising from endometriosis is exceedingly rare. The accuracy of diagnosing endometriosis and ruling out neoplasm requires coordinated efforts of a multidisciplinary team, involving radiologists, pathologists, oncologists, and gynecologic surgeons. PMID: 31624455 [PubMed - in process]
Source: JSLS : Journal of the Society of Laparoendoscopic Surgeons - Category: Surgery Tags: JSLS Source Type: research
Authors: Abstract Hazardous drugs (HDs) are chemicals that demonstrate one or more of the following characteristics: carcinogenicity, genotoxicity, teratogenicity, reproductive toxicity, or organ toxicity. In addition, newer drugs with a structural or toxicity profile that mimics an agent known to be hazardous by one of the aforementioned criteria also should be treated as such. Any HD-handling activity can result in exposure for healthcare workers, as documented in a multitude of case reports and studies throughout the medical literature. Exposure to HDs has been associated with acute symptoms (e.g., nasal sores...
Source: Oncology Nursing Forum - Category: Nursing Tags: Oncol Nurs Forum Source Type: research
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
AbstractBackgroundTo date, some factors associated with quality of sleep in patients with PCOS have been identified. Previous studies have mainly focused on limited psychological variables related to sleep disorder without evaluating them in a comprehensive framework.ObjectiveThe aim of the present study was to evaluate the impact of predictive factors on the sleep quality of PCOS patients using structural equation modeling (SEM).Material and methodsThe present study is a case control that is done in an infertility clinic in Hormozgan, Iran. The case group (n = 201) consisted of women with PCOS and the contro...
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
ConclusionsThe study outcome strongly suggests that compromised semen quality is associated with increased rates of mosaic blastocysts analysed in PGT-A cycles. Sperm assessment appears therefore as an important factor in the determination of embryo development and for a more precise prognostic assessment of PGT-A cases.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
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