Treatment with the Long-acting Insulin Analog Degludec During Pregnancy in Women with Type 1 Diabetes: An Observational Study of 22 Cases

Type 1 diabetes in pregnancy is associated with increased risk of maternal and offspring complications such as congenital malformations, preeclampsia, preterm delivery, macrosomia, perinatal morbidity and mortality [1 –3]. Moreover, offspring born to women with type 1 diabetes have a long-term increased risk of obesity and type 2 diabetes [1–4]. Tight glycemic control at the time of conception and during pregnancy is mandatory to reduce the risk of adverse outcomes, though maternal severe hypoglycemia is a ma jor barrier in achieving this goal [5].

Source: Diabetes Research and Clinical Practice - May 14, 2019 Category: Endocrinology Authors: Maria Fredsgaard Keller, Marianne Vestgaard, Peter Damm, Elisabeth Reinhardt Mathiesen, Lene Ringholm Source Type: research