Total synthesis of Escherichia coli with a recoded genome

Nature, Published online: 15 May 2019; doi:10.1038/s41586-019-1192-5High-fidelity convergent total synthesis is used to produce Escherichia coli with a 61-codon synthetic genome that uses 59 codons to encode all of the canonical amino acids.

Source: Nature AOP - May 14, 2019 Category: Research Authors: Julius Fredens Kaihang Wang Daniel de la Torre Louise F. H. Funke Wesley E. Robertson Yonka Christova Tiongsun Chia Wolfgang H. Schmied Daniel L. Dunkelmann V áclav Beránek Chayasith Uttamapinant Andres Gonzalez Llamazares Thomas S. Elliott Jason W. Chi Source Type: research