Transcription factors and 3D genome conformation in cell-fate decisions

Nature, Published online: 15 May 2019; doi:10.1038/s41586-019-1182-7Three-dimensional genome architecture has important roles in the regulation of gene expression and is therefore a key determinant of cell identity in normal development and in disease states.

Source: Nature AOP - May 14, 2019 Category: Research Authors: Ralph Stadhouders Guillaume J. Filion Thomas Graf Source Type: research