Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours

ConclusionsUCP1 is strongly expressed in BAT but not WAT and is found in all hibernomas and a few pleomorphic liposarcomas but not in other adipose tumours. UCP1 expression in a few non-adipose soft tissue sarcomas may possibly reflect origin of tumour cells from a common mesenchymal stem cell precursor and/or developmental pathway.
Source: Clinical Sarcoma Research - Category: Cancer & Oncology Source Type: research