Contents: Evolution ’s Clinical Guidebook: Translating Ancient Genes Into Precision Medicine

In yesterday ' s blog, I announced the publication of my book,Evolution ’s Clinical Guidebook: Translating Ancient Genes Into Precision Medicine. The premise of this book is that modern medicine is based on an understanding of evolutionary processes. Basically, without evolution, the fledgling field of precision medicine would wither and die, and we would lose our opportunity to prevent, diagnose, and treat the diseases that account for the bulk of morbidity and mortality in humans and in animals.This book is available fromAmazon or from thepublisher ' s website. If you are fortunate enough to have full institutional access to ScienceDirect, you can download chapters at no cost. Here is the Table of Contents.Contents: Evolution ’s Clinical Guidebook: Translating Ancient Genes into Precision Medicine1. Evolution, From the Beginning 1Section 1.1 In the Beginning 1Section 1.2 Bootstrapping Paradoxes 5Section 1.3 Our Genes, for the Most Part,Come From Ancestral Species 12Section 1.4 How do Metabolic Pathways Evolve? 15Section 1.5 Cambrian Explosion 21Section 1.6 After the Cambrian: Coexistenceand Coevolution 25Glossary 29References 442. Shaking Up the Genome 51Section 2.1 Mutation Burden 51Section 2.2 Gene Pools and Gene Conservation 58Section 2.3 Recombination and OtherGenetic Tricks 61Section 2.4 Genomic Architecture:An Evolutionary Free-for-All 64Section 2.5 Rummaging Through the DNA Junkyard 73Glossary 77References 873. Evolution and Embryonic Development 93Section 3.1 Th...
Source: Specified Life - Category: Information Technology Tags: bioinformatics clinical genetics evo-devo evolution precision medicine rare disease Source Type: blogs