China tests brain implants to treat opioid addiction
The deep brain stimulation treatment involves a surgeon drilling two small holes in the skull and feeding electrodes deep into the brain
Authors: Beszłej JA, Wieczorek T, Kobyłko A, Piotrowski P, Siwicki D, Weiser A, Fila-Witecka K, Rymaszewska J, Tabakow P Abstract Deep brain stimulation (DBS) is a treatment method that is currently getting more and more attention from psychiatrists. It has proven to be efficacious and safe in the treatment of neurological disorders, mainly Parkinson's disease (PD), dystonia and essential tremor. DBS has very often contributed to successful treatment in cases that had proved resistant to all other methods of treatment. Nowadays treatment-resistant obsessive-compulsive disorder (OCD) is the main psychiatric indica...
We present a brief review on a novel neuromodulation target of the nucleus accumbens (NA) and its promising role in the management of addiction. The three stages of the addiction cycle are known to be mediated by dopaminergic pathways located in the mesolimbic dopamine system with connections to dorsal striatum, extended amygdala, cingulate gyrus, orbitofrontal cortex, prefrontal cortex, and ventral tegmental area. Recent advanced neuroimaging in humans and several animal studies demonstrated NA to be a vital anatomical area modulating this network. DBS of NA in animals reduced addictive behavior to alcohol, cocaine, and o...
https://www.washingtonpost.com/health/surgeon-implants-electrodes-in-patients-brain-in-attempt-to-cure-severe-opioid-use-disorder/2019/11/06/b76bdea8-0000-11ea-8501-2a7123a38c58_story.html The next CornerLoc, SI-Fuse?
It’s the first time electrodes have been implanted in the brain for opioid use disorder in the United States.
Substance use disorders (SUDs) are a growing public health concern with only a limited number of approved treatments. However, even approved treatments are subject to limited efficacy with high long-term relapse rates. Current treatment approaches are typically a combination of pharmacotherapies and behavioral counselling. Growing evidence and technological advances suggest the potential of brain stimulation techniques for the treatment of SUDs. There are three main brain stimulation techniques that are outlined in this review: transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and dee...
Read the latest on deep brain stimulation for addiction treatment, machine learning to predict cardiovascular events, and unusual eyelash growth after cancer treatment.Medscape
Condition: Addiction Opiate Intervention: Procedure: Bilateral surgical implantation of DBS system to Nucleus Accumbens Sponsor: Ruijin Hospital Recruiting