Final LATITUDE Results Confirm Previous Findings for High-Risk Prostate Cancer

Final results of LATITUDE confirm the beneft of abiraterone acetate plus prednisone along with ADT in high-risk metastatic castration-sensitive prostate cancer.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news

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AbstractBackgroundRadiomics can provide quantitative features from medical imaging that can be correlated with various biological features and clinical endpoints. Delta radiomics, on the other hand, consists in the analysis of feature variation at different acquisition time points, usually before and after therapy. The aim of this study was to provide a systematic review of the different delta radiomics approaches.MethodsEligible articles were searched in Embase, PubMed, and ScienceDirect using a search string that included free text and/or Medical Subject Headings (MeSH) with three key search terms: “radiomics&rdquo...
Source: La Radiologia Medica - Category: Radiology Source Type: research
Cell Death &Disease, Published online: 04 December 2021; doi:10.1038/s41419-021-04421-0Exosomal long noncoding RNA HOXD-AS1 promotes prostate cancer metastasis via miR-361-5p/FOXM1 axis
Source: Cell death and disease - Category: Internal Medicine Authors: Source Type: research
Prostate cancer is the most common malignant tumor in men. Due to the lack of theoretical research on its pathogenic mechanism, the current cure rate is still low. miRNAs play an important role in the pathogen...
Source: World Journal of Surgical Oncology - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
CONCLUSION: SET7/9 is an important methyltransferase, which can catalyze the methylation of a variety of proteins. Its substrates are closely related to the occurrence and development of tumors.PMID:34856916 | DOI:10.2174/1574892816666211202160041
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
CONCLUSIONS: Increased miRNA-153 expression and lost PTEN expression in PCa may provide information on their role in the progression of this cancer, suggesting that miRNA-153 could affect PTEN directly in prostatic neoplastic and hyperplastic lesions, and therefore miRNA-153 can be considered a new tool to improve the treatment efficacy and prognosis of PCa patients.PMID:34859846 | DOI:10.26355/eurrev_202111_27231
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Source Type: research
Br J Radiol. 2021 Dec 3:20210563. doi: 10.1259/bjr.20210563. Online ahead of print.ABSTRACTProstate cancer (PCa) is the most common cancer type in males in the Western World. MRI has an established role in diagnosis of PCa through guiding biopsies. Due to multistep complex nature of the MRI-guided PCa diagnosis pathway, diagnostic performance has a big variation. Developing artificial intelligence (AI) models using machine learning, particularly deep learning, has an expanding role in radiology. Specifically, for prostate MRI, several AI approaches have been defined in the literature for prostate segmentation, lesion detec...
Source: The British Journal of Radiology - Category: Radiology Authors: Source Type: research
CONCLUSION: SET7/9 is an important methyltransferase, which can catalyze the methylation of a variety of proteins. Its substrates are closely related to the occurrence and development of tumors.PMID:34856916 | DOI:10.2174/1574892816666211202160041
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
CONCLUSIONS: Increased miRNA-153 expression and lost PTEN expression in PCa may provide information on their role in the progression of this cancer, suggesting that miRNA-153 could affect PTEN directly in prostatic neoplastic and hyperplastic lesions, and therefore miRNA-153 can be considered a new tool to improve the treatment efficacy and prognosis of PCa patients.PMID:34859846 | DOI:10.26355/eurrev_202111_27231
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Source Type: research
CONCLUSIONS: Growing evidence support the association between metabolic syndrome and prostate cancer, bias derived from observational studies might conceal further findings.PMID:34859640 | DOI:10.23736/S0031-0808.21.04507-9
Source: Panminerva Medica - Category: General Medicine Authors: Source Type: research
Br J Radiol. 2021 Dec 3:20210563. doi: 10.1259/bjr.20210563. Online ahead of print.ABSTRACTProstate cancer (PCa) is the most common cancer type in males in the Western World. MRI has an established role in diagnosis of PCa through guiding biopsies. Due to multistep complex nature of the MRI-guided PCa diagnosis pathway, diagnostic performance has a big variation. Developing artificial intelligence (AI) models using machine learning, particularly deep learning, has an expanding role in radiology. Specifically, for prostate MRI, several AI approaches have been defined in the literature for prostate segmentation, lesion detec...
Source: The British Journal of Radiology - Category: Radiology Authors: Source Type: research
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