Arsenic exposure and serum antibody concentrations to diphtheria and tetanus toxoid in children at age 5: A prospective birth cohort in Bangladesh.

CONCLUSIONS: Among vaccinated children, W-As measured during pregnancy was associated with decreased diphtheria antibody levels, but not tetanus antibody. However, W-As measured during toddlerhood and early childhood were not associated with either antibody outcome. Children's sex and malnutrition status were important effect modifiers of W-As for both diphtheria and tetanus antibody levels, highlighting the importance of these factors and the timing of the exposure when evaluating the effect of arsenic on humoral immunity.
PMID: 31051324 [PubMed - as supplied by publisher]

Source: Environment International - April 29, 2019 Category: Environmental Health Authors: Welch BM, Branscum A, Ahmed SM, Hystad P, Smit E, Afroz S, Megowan M, Golam M, Ibne Hasan MOS, Rahman ML, Quamruzzaman Q, Christiani DC, Kile ML Tags: Environ Int Source Type: research