Blue Earth touts presentations at AUA 2019

Molecular imaging firm Blue Earth Diagnostics is highlighting several presentations...Read more on AuntMinnie.comRelated Reading: Blue Earth study reports Axumin can aid glioma diagnosis Blue Earth promotes results for PET/CT agent Blue Earth expands PSMA-PET/CT imaging portfolio Blue Earth touts addition of Axumin to NCCN guidelines Blue Earth highlights Axumin clinical results at ASTRO
Source: Headlines - Category: Radiology Source Type: news

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Altered miRNA expression participates in the biological progress of thyroid carcinoma and functions as a diagnostic marker or therapeutic agent. However, the role of miR-7-2-3p is currently unclear. The authors' study was the first investigation of miR-7-2-3p expression level and diagnostic ability in several public databases. Potential target genes were obtained from DIANA Tools, and function enrichment analysis was then performed. Furthermore, the authors examined expression levels of potential targets in the Human Protein Atlas (HPA) and the Cancer Genome Atlas (TCGA). Finally, the potential transcription factors (TFs) ...
Source: IET Systems Biology - Category: Biology Source Type: research
Previous central nervous systems Oncology Scan articles in this publication have discussed treatment and molecular characterization of low-,1 intermediate-,2 and high-grade3,4 gliomas, controversies in the management of brain metastases,5-8 and evolving approaches to atypical meningiomas.9 Although arteriovenous malformations (AVMs) are nononcologic entities, optimal management of patients with this disease presents many of the same questions involved in the treatment of low-grade tumors: when, whom, or even if to treat.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Feature Source Type: research
Pediatric optic pathway glioma (POPG) is frequently treated with radiotherapy (RT). We evaluated the radiographic response and clinical outcomes after proton therapy (PBT).
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
Review for outcomes of re-irradiation(reRT) in Diffuse Intrinsic Pontine Glioma (DIPG).
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
Publication date: Available online 22 October 2019Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Muhammad Younis, Wang Faming, Zhao Hongyan, Tan Mengmeng, Song Hang, Yuan LiudiAbstractGlioma is the most common neoplasm of the central nervous system, with the highest mortality rate. The present study was designed to examine the therapeutic effect of Iguratimod (IGU) encapsulated- poly (lactic-co-glycolic acid) PLGA nanoparticles (IGU-PLGA-NPs), which showed inhibition of glioma cells proliferation both in vitro and in vivo. IGU was encapsulated in PLGA nanoparticles with an average size of 100-200 nm w...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Publication date: Available online 21 October 2019Source: Journal of Clinical NeuroscienceAuthor(s): Stephen Bacchi, Toby Zerner, John Dongas, Adon Toru Asahina, Amal Abou-Hamden, Sophia Otto, Luke Oakden-Rayner, Sandy PatelAbstractThe identification of high-grade glioma (HGG) progression may pose a diagnostic dilemma due to similar appearances of treatment-related changes (TRC) (e.g. pseudoprogression or radionecrosis). Deep learning (DL) may be able to assist with this task. MRI scans from consecutive patients with histologically confirmed HGG (grade 3 or 4) were reviewed. Scans for which recurrence or TRC was queried we...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
A comparison of two gadolinium-based contrast agents (GBCAs) for hepatobiliary...Read more on AuntMinnie.comRelated Reading: Ga-68 PSMA PET/MRI, mpMRI work for prostate cancer analysis Study shines more light on GBCA-related adverse reactions Gadolinium in gliomas, adjacent tissue raises questions German study may offer new way to detect gadolinium FDA adds 8 gadolinium MRI agents to medication guide
Source: Headlines - Category: Radiology Source Type: news
ConclusionsSpinal LGG is a rare entity with significant long-term effects. Although surgery is the most common initial treatment option, more in-depth analysis of molecular biomarkers may improve stratification and prognostication.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
AbstractPurposeReducing the time from surgery to adjuvant chemoradiation, by decreasing unnecessary readmissions, is paramount for patients undergoing glioma surgery. The effects of intraoperative risk factors on 30-day readmission rates for such patients is currently unclear. We utilized a predictive model-driven approach to assess the impact of intraoperative  factors on 30-day readmission rates for the cranial glioma patient.MethodsRetrospectively, the intraoperative records of 290 patients who underwent glioma surgery at a single institution by a single surgeon were assessed. Data on operative variables including ...
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
In this study, biotinylated PAMAM G3 dendrimers substituted with the recognized anticancer agents cyclooxygenase-2 (COX-2) inhibitor celecoxib and peroxisome proliferator-activated receptor γ (PPARγ) agonist Fmoc-L-Leucine (G3-BCL) were tested in vitro on human cell lines with different p53 status: glioblastoma (U-118 MG), normal fibroblasts (BJ) and immortalized keratinocytes (HaCaT). G3-BCL penetrated efficiently into the lysosomal and mitochondrial compartments of U-118 MG cells and induced death of U-118 MG cells via apoptosis and inhibited proliferation and migration at low IC50 = 1.25 µM...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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