Alveolar concentration of nitric oxide as a prognostic biomarker in idiopathic pulmonary fibrosis

ConclusionWe confirm that CaNO was significantly higher in IPF patients than in healthy controls and its correlation with functional parameters. Moreover, CaNO ≥6 and ≥9 ppb were significantly correlated with mortality and disease progression, respectively. These data suggest that CaNO, a non-invasive and reproducible biomarker, may predict disease progression and survival outcome in patients with IPF.
Source: Nitric Oxide - Category: Chemistry Source Type: research