Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: is there a difference?

CONCLUSIONS: Eloctate and Adynovate have almost identical PK parameters. When switching from one to another no prophylaxis regimen change is needed. This article is protected by copyright. All rights reserved. PMID: 31038793 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31038793?dopt=Abstract

Source: Thrombosis and Haemostasis - April 29, 2019 Category: Hematology Authors: Carcao MD, Chelle P, Clarke E, Kim L, Tiseo L, Morfini M, Hossain T, Rand ML, Brown C, Edginton A, Lillicrap D, Iorio A, Blanchette VS Tags: J Thromb Haemost Source Type: research