Drug-Induced Liver Injury by Sevoflurane and Desflurane Drug-Induced Liver Injury by Sevoflurane and Desflurane

Have modern volatile anesthetics reduced the incidence of drug-induced liver injury compared to that reported with older agents?Alimentary Pharmacology &Therapeutics
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

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CONCLUSIONS: Interdisciplinary team-based care providing accurate diagnostic services, coordinated planning, and safer surgery deliver effective care with improved clinical outcomes in comparison with alternative management. SUMMARY STATEMENTS: RECOMMENDATIONS. PMID: 31227057 [PubMed - in process]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Conclusions: These results indicate a link between Shh and autophagy in the rat model of POCD, providing new insights into Shh signaling pathway-mediated mechanisms of neuroprotection and cognitive repair after POCD. It also provides a potential entry point for the development of clinical drugs. PMID: 31221056 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Authors: Niyyar VD Abstract Sonography is increasingly being used by nephrologists and the field of dialysis access is no exception. Advances in technology have allowed the addition of this universally available, portable, non-invasive tool to the nephrologist's armamentarium, which provides information on both morphology and physiology without the need for contrast or radiation. Ultrasound may be used across the spectrum of dialysis access, including central venous catheter placements, vascular mapping, regional anesthesia, creation, maintenance and assessment of hemodialysis access as well as assessment of the ab...
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Hi everyone, in the future I want to work in surgery or maybe anesthesia. I had planned on applying to PA school but right now I am not the strongest applicant . I had planned working over the next year and retaking classes, then applying to PA school next application cycle. But, a few weeks ago I was accepted to an accelerated BSN program. I had never really planned on being an RN, but if I did this program I could then go out and gain really valuable patient care hours. The only... RN program or wait an application cycle?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Clinicians [ RN / NP / PA ] Source Type: forums
Madigan must pay $12.3M in operating-room fire that disfigured child The child was undergoing a routine procedure to remove a cyst from his forehead when a surgeon's electric scalpel ignited a high-concentration of oxygen being used by an anesthesiologist, engulfing the child's boy's face in a fireball and disfiguring him... www.seattletimes.com Madigan again. SDN wouldn’t let me necro the last Madigan malpractice thread
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Military Medicine Source Type: forums
Pediatric gastroenterologists recommend and perform a range of procedures requiring sedation and anesthesia in young children. A recent warning from the US Food and Drug Administration (FDA) states that “repeated or lengthy use of general anesthetics and sedation drugs during surgeries or procedures in children younger than 3 years or in pregnant women during their third trimester may affect the development of children's brains.” 1 As it relates to time, the FDA warning details risks of “procedures lasting longer than 3 hours or if multiple procedures are required.” Pediatric gastroenterologists a...
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Topic of the Month Source Type: research
CONCLUSIONS: Age, anesthetic risk, presence of hydronephrosis, pT and pN stage were identified as independent predictors of GM, as well as pT and pN stage for CSM. PMID: 31223123 [PubMed - in process]
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research
Authors: Lee S Abstract Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties. Dexmedetomidine induces a unique sedative response which shows easy transition from sleep to wakefulness, allowing a patient to be cooperative and communicative when stimulated. Dexmedetomidine may produce less delirium compared with other sedatives, or even prevent delirium. Analgesic effect of dexmedetomidine is not strong, however, it can be administered as a useful analgesic adjuvant. Dexmedetomidine decreases the need for opioi...
Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research
Authors: Na SH, Shin CS, Kim GH, Kim JH, Lee JS Abstract Background: The long-term outcomes of patients discharged from the hospital after successful care in intensive care unit (ICU) are not briskly evaluated in Korea. The aim of this study was to assess long-term mortality of patients treated in the ICU and discharged alive from the hospital and to identify predictive factors of mortality. Methods: In 3679 adult patients discharged alive from the hospital after ICU care between 2006 and 2011, 1-year mortality rate (primary outcome measure) was investigated. Various factors were entered into multivariate analy...
Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research
Vasectomy is the safest and most cost-effective means of long-term permanent contraception, and is easily and safely performed in the office setting, under local anesthesia. Although some patient factors, such as body habitus, prior failed vasectomy, or extreme anxiety, may warrant consideration of vasectomy under sedation, these instances are infrequent and cannot account for the finding that approximately 18% of all vasectomies were performed in the ambulatory surgery center (ASC setting) during the study period.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
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