Comorbidities and the impact of atopic dermatitis.
Comorbidities and the impact of atopic dermatitis. Ann Allergy Asthma Immunol. 2019 Apr 26;: Authors: Silverberg JI PMID: 31034875 [PubMed - as supplied by publisher]
Authors: Čepelak I, Dodig S, Pavić I Abstract There is an increasing number of experimental, genetic and clinical evidence of atopic dermatitis expression as a pre-condition for later development of other atopic diseases such as asthma, food allergy and allergic rhinitis. Atopic dermatitis is a heterogeneous, recurrent childhood disease, also present in the adult age. It is increasingly attributed to systemic features and is characterized by immunological and skin barrier integrity and function dysregulation. To maintain the protective function of the skin barrier, in particular the maintenance of pH, hydration a...
The prevalence of allergic diseases such as asthma, allergic rhinitis, food allergy and atopic dermatitis has increased dramatically in recent decades. Conventional therapies for allergy can induce undesirable effects and hence patients tend to seek for natural compounds as alternative medicine. Considering the fact above, there is an urgency to discover potential medicinal plants as future candidates in the development of novel anti-allergic therapeutic agents. Lamiaceae family, the mint family, is a diverse plant family which encompasses more than 7000 species and with a cosmopolitan distribution. A number of species fro...
Conclusion: The unaffected siblings of ADHD probands were more likely to develop atopic diseases compared with the controls, suggesting shared risk factors for both diseases.Int Arch Allergy Immunol
JI Silverberg had full access to all the data in the study and takes responsibility for the integrity of the data and accuracy of the data analysis. Study concept and design: JI Silverberg Acquisition of Data: JI Silverberg, BT Cheng Analysis and interpretation of data: BT Cheng, JI Silverberg, Drafting of the manuscript: BT Cheng, JI Silverberg Critical revision of the manuscript for important intellectual content: BT Cheng, JI Silverberg Statistical analysis: JI Silverberg, BT Cheng
PMID: 31201863 [PubMed - as supplied by publisher]
CONCLUSIONS: Our results demonstrate that the combination of TECA and AST could be a promising therapeutic agent for AD by inhibiting NF-κB signaling. PMID: 31172723 [PubMed]
This study aimed to describe clinical characteristics and to identify prognostic factors associated with tolerance acquisition of immunoglobulin E (IgE)-mediated egg allergy in children. METHODS: Children who underwent more than 1 follow-up egg white-specific immunoglobulin E (EWsIgE) test between November 2005 and November 2015 at -Severance Children's Hospital were assessed. Children were diagnosed as having IgE-mediated egg allergy based on immediate allergic reaction after egg consumption and an EWsIgE level of> 0.35 kU/L. The children were divided into "tolerant" and "persistent" groups acco...
CONCLUSIONS: Egg allergy was outgrown in 72.2% and peanut allergy in 15.8% of SA children 5 years after diagnosis of AD. This is in keeping with findings derived from studies in higher socioeconomic settings, and can help to guide the counselling of patients with allergies to these foods of high nutritional value. PMID: 31131799 [PubMed - in process]
Abstract BACKGROUND: Atopic dermatitis (AD) represents the most common chronic inflammatory skin disease in childhood. Few data are available about the different AD phenotypes and their nationwide distribution. METHODS: We performed a cross-sectional multicentre study involving some of the main Italian paediatric allergy centres in 9 Italian cities. A structured questionnaire was administered to 371 children with AD. Patients were divided in two groups: preschool children (aged
Publication date: Available online 23 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Hyun Yong Koh, Tae Hwan Kim, Youn Ho Sheen, Seung Won Lee, Jaewoo An, Mi Ae Kim, Man Yong Han, Dong Keon Yon