005 Elucidating the mechanism(s) of silica nanoparticle induced immunomodulation in contact hypersensitivity

Nanoparticle (NP) enabled consumer products and biomedical devices have become ubiquitous. Many examples exist of NP based products in the cosmetic, sunscreen, and textile industries. While currently used as an anti-caking agent in cosmetics and foods, silica NPs have been the focus of numerous transdermal drug delivery studies, which can lead to increased dermal exposure. Research on the lungs and gastrointestinal tract have highlighted a potential immunomodulatory capacity of NPs; however, additional research into the health effects of NPs on skin are warranted.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Adaptive and Auto-Immunity Source Type: research