Cryptococcal meningitis after ART: Need for proper baseline evaluation in the era of ‘Test & Treat’

We report a case of severe cryptococcal meningitis presenting following the commencement of ART. There is clear benefit in the early commencement of ART among HIV infected patients and to prevent patients lost to follow-up as aimed with the ‘Test & Treat’ approach. However, this approach needs to be balanced against the risk of IRIS and its associated morbidity and mortality when those patients are not being properly evaluated for opportunistic infections being present without overt symptoms.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research