Management of metastatic bladder cancer

Bladder cancer is among the most prevalent cancers worldwide, with around 430,000 new diagnoses each year [1]. Most UC develops in the urinary bladder and is derived from the pseudostratified epithelium known as the urothelium. Considerably fewer UCs develop in the renal pelvis and ureter (upper tract), which are also lined by urothelium. Tumors that invade the detrusor muscle are considered muscle-invasive bladder cancer (MIBC) and are more likely to metastasize to lymph nodes or other organs. Approximately 75% of newly diagnosed patients have non-muscle-invasive bladder cancer with the remaining 25% having MIBC [2] or metastatic disease [3].
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Tumour Review Source Type: research