Stimulating Type 1 Angiotensin Receptors on T Lymphocytes Attenuates Renal Fibrosis

In this study, mice with T-cell –specific deletion of the dominant murine AT1 receptor isoform Lck-Cre Agtraflox/flox [total knockout (TKO)] and wild-type (WT) controls were subjected to the unilateral ureteral obstruction model of kidney fibrosis.

Source: American Journal of Pathology - April 14, 2019 Category: Pathology Authors: Yi Wen, Nathan P. Rudemiller, Jiandong Zhang, Alexander D. Jeffs, Robert Griffiths, Xiaohan Lu, Jiafa Ren, Jamie Privratsky, Steven D. Crowley Tags: Short communication Source Type: research