Comment on “The Enhancing Effect of Focused Ultrasound on TNK-Tissue Plasminogen Activator-Induced Thrombolysis Using an In Vitro circulating Flow Model”

The objective of the study by Papadopoulos et al. was to evaluate the effect of various parameters such as temperature, focused ultrasound (FUS) energy, FUS frequency, acoustic power, and microbubble administration on tenecteplase (TNK)-tissue plasminogen activator-mediated thrombolysis and therefore, to establish a treatment protocol that maximize thrombolysis efficacy. For this purpose, an in vitro circulating flow clot model was designed to reproduce a middle cerebral artery occlusion.

Source: Journal of Stroke and Cerebrovascular Diseases - April 12, 2019 Category: Neurology Authors: Nicolas Papadopoulos, Christakis Damianou Tags: Letter to the Editor Source Type: research