Targeting High Mobility Group Box-1 (HMGB1) Promotes Cell Death in Myelodysplastic Syndrome.

CONCLUSIONS: Inhibition of HMGB1 could promote MDS cell death and alter innate immune responses via suppression of NFkB pathways.
PMID: 30952643 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - April 4, 2019 Category: Cancer & Oncology Authors: Kam AYF, Piryani SO, McCall CM, Park HS, Rizzieri DA, Doan PL Tags: Clin Cancer Res Source Type: research