Development and validation of Sasang Urination and Defecation Inventory (SUDI) for pathophysiological symptoms of Sasang typology
DiscussionThe pathophysiological symptoms of urination and defecation in Sasang typology were systematically scrutinized, and summarized into six subscales of SUDI in this study. The SUDI would be useful for analyzing clinical symptoms of Sasang typology along with integrative collaboration of traditional Korean and Western medicine.
Called “small intestinal bacterial overgrowth,” the condition happens when otherwise good bacteria ends up in the wrong part of the digestive system.
Background: Irritable bowel syndrome (IBS) is a stress-sensitive disorder of brain-gut interactions associated with a higher prevalence of early adverse life events (EALs). However, it is incompletely understood how trauma severity or disclosure influence the risk of developing IBS or symptom severity. Aims: To determine whether (1) IBS patients report a greater number of EALs compared with healthy controls; (2) trauma severity and first age of EAL increase the odds of IBS; (3) confiding in others reduces the odds of IBS; (4) the number, trauma severity, and first age of EAL are associated with symptom severity; (5) s...
ConclusionPhysically active women who lift heavy weights for exercise do not have an increased prevalence of POP symptoms. Advice on the contribution of heavy weight lifting as part of a physical activity regime to the pathophysiology of POP requires further investigation.
ConclusionsAltogether, these findings establish that urinary metabolites of mitochondrial dysfunction, ketosis and oxidative stress can be potential biomarkers of OAB severity and diagnosis.
ConclusionsWe found no changes in MOCA scores between OAB medication and control groups after controlling for age, depression, and polypharmacy after 12 months of follow-up.
Overactive bladder is a common and bothersome condition which has a major and measurable impact on sufferers' quality of life. The cardinal symptom of urgency, with or without urgency incontinence, frequency and nocturia is thought to be caused by abnormalities in detrusor smooth muscle function and/or sensory pathways. A structured assessment approach is of importance, including a detailed history of symptoms, medical and drug history and lifestyle factors such as fluid intake. Conservative management revolves around the key principles of fluid modification, avoidance of potential triggers and bladder retraining.
CONCLUSIONS: In this cohort of women with vulvar diseases, vitamin D levels and supplementation were not significantly different amongst women with vulvar lichen sclerosus or other non-lichenoid vulvar diseases. Furthermore, vitamin D levels are not serum biomarkers for OAB, urinary incontinence, constipation, or IBS. PMID: 30747611 [PubMed - as supplied by publisher]
ConclusionsThe overall work productivity impairment as a result of nocturia is substantial and was found to be similar to impairment observed as a result of several other more frequently researched common chronic diseases. Greater awareness of the burden of nocturia, a highly bothersome and prevalent condition, will help policy makers and healthcare decision makers provide appropriate management of nocturia.
CONCLUSIONS: OAB is a frequent syndrome. Its prevalence increases with age, and OAB frequently concern elderly frail people with many other associated diseases. LEVEL OF EVIDENCE: 3. PMID: 27108102 [PubMed - as supplied by publisher]
This study aims to compare the prevalences of lower urinary tract symptoms (LUTS), irritable bowel syndrome (IBS) and constipation in women with vulvar diseases to those from the general population. Methods: Three groups of women were recruited from the University of Michigan Gynecology Clinics, women with: (1) biopsy proven lichen sclerosus (LS), (2) non-LS vulvar diseases (vulvar controls, VC), and (3) presenting for annual examinations (AE). All patients completed self-administered surveys and validated pelvic floor symptom questionnaires. Results: 317 subjects were enrolled: 101 with LS, 86 VCs, and 130 AEs. Compared t...