Outcomes of Reinterventions for Children with Postoperative Pulmonary Venous Restenosis

This report aims to summarize  and evaluate the efficacy and experience of reintervention for children with postoperative pulmonary venous restenosis. Clinical data from 61 patients with postoperative pulmonary venous restenosis who underwent reintervention at Shanghai Children’s Medical Center (SCMC) from September 2009 t o June 2018 were retrospectively analyzed. The patients comprised 38 boys and 23 girls, with a mean age of 15.4 ± 12.6 months (2-83 months) and a mean weight of 8.1 ± 3.4 kg (3.7–18.5 kg). The mean pulmonary venous velocity was 2.31 ± 0.47 m/s (1.86–3.22 m/s). Primary disea se included 48 cases of total anomalous pulmonary venous drainage, nine cases of partial anomalous pulmonary venous drainage, and four cases of primary pulmonary venous stenosis. The reintervention procedures included 34 cases using the sutureless technique, ten cases using bovine pericardium enlarg ement, three cases using blunt enlargement, four cases of balloon dilatation, one case using stent implantation and nine cases involving more than two surgical methods. The early postoperative pulmonary venous velocity was 1.16 ± 0.20 m/s. There were five in-hospital deaths, resulting in a mo rtality rate of 8.2%. Fifty-six survivors were followed for 52.8 ± 46.5 months (6–103 months) with no delayed deaths. Echocardiography showed pulmonary venous anastomosis and diameter growth after reintervention, exhibiting a mean growth speed of 0.026 ±...

Source: Mammalian Genome - March 31, 2019 Category: Genetics & Stem Cells Source Type: research