Breaks and bends in sperm DNA: their impact on the future of the embryo

Conventional semen analysis parameters are not sufficient to evaluate male fertility potential and are not predictive of sperm function. Sperm DNA damage has been identified as a major contributor to male factor infertility and poor IVF outcome due to impaired embryo development. It increases time to pregnancy, hampers and increases the embryo cleavage time, increases miscarriage rates, increases the risk of pregnancy loss after IVF or intracytoplasmic sperm  injection (ICSI), and increases birth defects in the offspring (1).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research