At Age 71, She Has Never Felt Pain or Anxiety

Scientists discovered a previously unidentified genetic mutation in a Scottish woman. They hope it could lead to the development of new pain treatment.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Genetics and Heredity Opioids and Opiates Pain-Relieving Drugs Anxiety and Stress University College London Scotland Jo Cameron The British Journal of Anaesthesia Source Type: news

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When patients express fear and anxiety about dentistry, one main source involves the administration of local anesthetic. The Dentapen is a Computer-Controlled Local Anesthetic Device (CCLAD) that regulates the rate of anesthetic deposition to reduce pain associated with dental injections. The purpose of this study was to evaluate differences in perceived pain during the administration of local anesthesia of the maxillary lateral incisors using the ramp-up and continuous injection modes of the Dentapen.
Source: Journal of Endodontics - Category: Dentistry Authors: Tags: Clinical Research Source Type: research
TITUSVILLE, N.J. – (August 3, 2020) – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application (sNDA) for SPRAVATO® (esketamine) CIII nasal spray, taken with an oral antidepressant, to treat depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation orbehavior.1 SPRAVATO® is the first and only approved medicine that has been shown to reduce depressive symptoms within 24 hours,1 providing a new option for significant symptom relief until a longer-ter...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Purpose of review The present review provides an overview of the different fields of procedural sedation and analgesia (PSA), describing the evidence from recently published studies concerning anxiety and moderate pain, cardiac interventions, gastrointestinal interventions, and PSA use in infants. It also provides guidance for practitioners of both unscheduled and scheduled procedural sedation, and a summary of the current guideline for PSA. Recent findings Safety always has to be first priority. Recently published literature is focusing on the combination of different well established drugs such as dexmedetomidine, r...
Source: Current Opinion in Anaesthesiology - Category: Anesthesiology Tags: NONOPERATING ROOM ANESTHESIA: Edited by Janusz C. Andres Source Type: research
Conditions:   Music Therapy;   Perioperative Care;   Postoperative Pain;   Anxiety;   Total Knee Arthroplasty;   Vital Signs;   Spinal Anesthesia Interventions:   Other: music therapy;   Other: sedated group;   Other: non-sedated group Sponsor:   Abant Izzet Baysal University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study investigates the preoperative anxiety rate and its effect on anesthetic recovery and postoperative pain in patients undergoing donor nephrectomy. METHODS: Forty-eight individuals undergoing living-related renal donor nephrectomy were included in this analytic prospective observational cohort study. Their preoperative anxiety was measured with the STAI-I and STAI-II inventories. The relationships between anxiety scores with data regarding demographics, recovery from anesthesia, and postoperative pain scores were investigated. RESULTS: The findings were remarkable in that the anxiety scores of living renal...
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Authors: Boyle CA, Lane H Abstract When faced with an anxious patient with complex needs who requires dental care, it can be difficult to decide on the most appropriate method to manage their pain and anxiety. There are a range of conscious sedation techniques that may be used, and on some occasions, general anaesthesia may be required. This paper describes the methods available and the factors influencing the decision-making process. The general dental practitioner (GDP) may not be able to offer care in their setting, but knowing more about the decision-making process and the information required to make that deci...
Source: Primary dental care : journal of the Faculty of General Dental Practitioners UK - Category: Dentistry Tags: Prim Dent J Source Type: research
This study aims to determine if there is an association between caregiver's pre-operative anxiety and children's post-operative pain in a lower-middle income country (LMIC) setting. METHODS: In this cross-sectional, descriptive study, we recruited 76 children aged 4 to 12 years, undergoing elective ambulatory tonsillectomy or adenotonsillectomy. Primary caregivers completed validated measures of anxiety (the Beck Anxiety Inventory [BAI] and the Kessler Psychological Distress Scale [K10]) prior to the children undergoing surgery. Post-operative pain was measured using the Wong Baker Faces Pain Rating Scale 4 hours afte...
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Tags: Paediatr Anaesth Source Type: research
What is the connection between sexual abuse and developing an eating disorder? Why does bingeing, purging, starving and chronic dieting become a “solution” for the abuse? Abuse shatters the sacred innocence of a child and often becomes a primary trigger for an eating disorder. The survivor of sexual abuse becomes plagued with confusion, guilt, shame, fear, anxiety, self-punishment, and rage. She (or he) seeks the soothing comfort, protection, and anesthesia that food offers. Food, after all, is the most available, legal, socially sanctioned, cheapest mood altering drug on the market! And emotional eating is a m...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Abuse Eating Disorders Trauma Anorexia Binge Eating Bulimia Sexual Abuse Source Type: blogs
The purpose was to determine the effect of watching an informative video about mandibular third molar (M3M) removal on patient anxiety and hemodynamic parameters.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Anesthesia/TMJ disorders/facial pain Source Type: research
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