Influence of baseline glycemia on outcomes with insulin glargine use in patients uncontrolled on oral agents.

CONCLUSION: When adequate glycemic control is not achieved using OADs in patients with T2DM, initiating insulin glargine is generally less likely to elicit hypoglycemia than initiating NPH, premixed, or prandial insulins, and the benefit-risk balance supports initiating insulin rather than intensification of OAD therapy when baseline HbA1c level is ≥ 8.0%. PMID: 24918797 [PubMed - indexed for MEDLINE]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research