Vulvovaginal Discomfort Is Common in Both Premenopausal and Postmenopausal Women

Objectives We surveyed women from a primary care population to assess the prevalence of unreported vulvovaginal symptoms. Materials and Methods A random sample of women aged 18 to 84 years without a diagnosis of vulvovaginitis or vulvodynia in the past year were surveyed anonymously about prevalence and severity of vulvar and vaginal symptoms of itching, burning, irritation, vaginal discharge, vaginal dryness, and vulvovaginal pain in the past month. Women reporting at least 1 moderate-severe symptom were considered symptomatic. Demographic and clinical characteristics were compared between women with and without symptoms using Pearson's χ2 and Student's t test. Results Of 1,676 mailed surveys, 272 (16.2%) were returned. Respondents were primarily non-Hispanic (254, 93.4%), White (214, 78.7%), and English speaking (267, 98.2%). More than a third of women (107, 39.3%) reported 1 or more moderate-severe symptoms. Symptomatic women were younger (49 ± 14 years vs 54 ± 15 years, p = .004) and more likely to report a history of asthma (22% vs 12%, p = .028), eczema or seasonal allergies (56% vs 40%, p = .011), or a previous diagnosis of bacterial vaginosis or yeast (36% vs 15%, p
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Benign Vulvovaginal Disorders Source Type: research

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Of the 8,000 Californians who will contract Valley Fever this year, most will recover without treatment, and those with more serious cases will require an antifungal medication that clears the infection. But a few will experience a life-threatening form of the disease that ravages the body for reasons unknown.Now, an experimental treatment used by physicians atUCLA Mattel Children ’s Hospital that cured a 4-year-old boy may provide an explanation — and a method for manipulating the immune system to combat not just Valley Fever, but a host of infections.In February 2018, the Gonzalez-Martinez family traveled 200...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Discussion There are numerous microbial communities inhabited in the human body, which is critical to human health. The relationship between human microbiome and diseases received much attention from both medical and bioinformatics community recently. However, traditional methods to detect their association is costly and labor-intensive. Thus, we proposed here a new computational model called NBLPIHMDA to infer potential microbe-disease associations. NBLPIHMDA first combined known microbe-disease associations in HMDAD and the Gaussian interaction profile kernel similarity to construct disease similarity network and microb...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease isolated to the esophagus Food allergy is thought to play an important role in the pathophysiology of EOE. The aim of this study is to evaluate demographic features and sensitivity of patients with reference to common food allergens. Children with documented EoE were enlisted for this study. Skin prick test and patch test were done for all participants. Each test contained common food allergens. Other tests, such as evaluation of total IgE and eosinophil count, were also done. A total of 30 patients (the mean age of participants was 3&plu...
Source: Iranian Journal of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Iran J Allergy Asthma Immunol Source Type: research
We read with great interest the article by Vakharia et al1 in a recent issue of the Annals. The prospective study comprehensively addresses an overlooked aspect of the sensory symptoms associated with atopic dermatitis (AD). In 305 patients with AD, the study reported that pain was found in 42.7% and that 30.2% rated the cutaneous pain intensity as being moderate to very severe. This pain incidence is aligned with a previous study on the AD itch characteristics.2 Vakharia et al1 consistently found cutaneous pain to be associated with reduced quality of life (including: Patient-Oriented Eczema Measure, ItchyQOL, and Dermato...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Correspondence Source Type: research
Conclusions: Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685 Received: 19 June 2016 Revised: 07 June 2017 Accepted: 19 June 2017 Published: 13 September 2017 Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
We read with great interest the landmark article by Gaul1 in which 16 individuals with positive patch test results to nickel received additional patch testing to inorganic and organic substances and more than half developed multiple sensitivities after the primary nickel sensitization. Notably, the patients with multiple sensitivities had developed more extensive dermatoses, had higher recurrence rates (characterized by decreased pain sensation, uncontrollable pruritus, and chronic eczema), and required multiple hospitalizations.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Correspondence Source Type: research
As the spring weather approaches, many common winter infections recede. However, warmer temperatures can introduce a new set of health challenges. As trees and flowers bloom and grass grows, susceptible children will start to display symptoms of seasonal allergies, triggering flares of asthma and eczema. And, As children spend more time outdoors, parents also need to watch for exposure to ticks, poison ivy and excess sun. Here are a few tips to keeping your child healthy this spring. Seasonal allergies: What can you do? During allergy season: have your child bathe after spending time outdoors to ...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Health & Wellness Parenting allergies asthma Carolyn Sax conjunctivitis lyme disease sunburn Source Type: news
This holiday season we are all in search of the perfect gift. What is the one thing you truly desire? Don’t you think we all want it? What if you were handed a beautifully wrapped box containing a miraculous tool that caused dramatic weight loss without limiting calories or requiring exercise? What if this gift reduced appetite, shrunk belly fat, dropped your dress size into the single digits, and accomplished all of this while sparing you from a Biggest Loser sob fest? What if that same gift freed you from acid reflux, heartburn, bowel urgency, and diarrhea, but also improved mood, increased energy, deepened sleep, ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Dr. Davis Priceless Gift Weight loss Wheat allergy Wheat Belly Wheat Belly Lifestyle Wheat Belly Total Health Wheat Watch Wheat-Free Lifestyle Detox diabetes gluten gluten-free grain grains Source Type: blogs
This holiday season we are all in search of the perfect gift. What is the one thing you truly desire for yourself and your family? Don’t you think we all want it? What if you were handed a beautifully wrapped box containing a miraculous tool that caused dramatic weight loss without limiting calories or requiring exercise? What if this gift reduced appetite, shrunk belly fat, dropped your dress size into the single digits, and accomplished all of this while sparing you from a Biggest Loser sob fest? What if that same gift freed you from acid reflux, heartburn, bowel urgency, and diarrhea, but also improved mood, incre...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Dr. Davis Priceless Gift Weight loss Wheat allergy Wheat Belly Wheat Belly Lifestyle Wheat Belly Total Health Wheat Watch Wheat-Free Lifestyle Detox diabetes gluten gluten-free grain grains Source Type: blogs
One of the most overlooked aspects of healthy eating is incorporating probiotics into one's diet. The fact that probiotics are technically a form of bacteria tends to turn people off. However, there is bad bacteria and good bacteria, and probiotics are the latter. By recognizing that they are good bacteria and having a better understanding how probiotics work, you will see how useful they can be for your overall health. Here is a closer look at five of the many benefits of making probiotics a regular part of your diet. 1. Soothes Indigestion Probiotics have been shown to play a role in preventing and relieving various ty...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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