POET: No Late Failure With Oral Antibiotic for Endocarditis POET: No Late Failure With Oral Antibiotic for Endocarditis
Longer-term follow-up of patients with left-sided infectious endocarditis shows no delayed issues with an early switch to oral from IV antibiotics.Medscape Medical News
Liquid biopsyÂ has attracted a surge of companies that are trying to change the way cancer is detected and monitored. But the benefits of this new type of technology can - and should - seep into other disease categories. Redwood City, CA-based Karius, for example, is leveraging liquid biopsy technology to give doctors an upper hand on difficult-to-diagnose infectious diseases. New findingsÂ show the potential clinical utility of its the Karius Test to detect pathogens causing serious infections using a simple blood draw. This includes pathogens that are otherwise difficult to culture or identify witho...
CONCLUSION: In patients with vascular prostheses, Propionibacterium acnes infection must be evoked face to an atypical inflammatory process. Very prolonged blood culture incubation is needed to identify the pathogen. PMID: 31229357 [PubMed - as supplied by publisher]
This study aimed to define the impact of DM on long-term mortality in IE patients. A total of 412 patients with definite IE from February 1999 to June 2012 were enrolled in this observational study and divided into 2 groups: group 1, patients with DM (n = 72) and group 2, patients without DM (n = 340). The overall in-hospital mortality rate for both groups combined was 20.2% and was higher in group 1 than in group 2 (41.7% vs. 16.5%, p < 0.01). Compared to patients without DM, patients with DM were older and associated with higher incidence of chronic diseases, less drug abuse, higher creatinine levels, and increase...
Background: Q fever infection by Coxiella Burnetii was discovered in Australia in 1935. Q fever endocarditis is rare and usually affects patients with native valve abnormalities or those with valve replacements. Diagnosis is difficult as infection is often culture negative. We investigated reported cases of Q fever endocarditis in the literature from 1967 to 2017.
AbstractThe authors report a case ofAspergillus aortitis and aortic valve endocarditis that developed after coronary artery bypass surgery resulting in recurrent, embolic, bilateral lower extremity ischemia. This necessitated multiple lower extremity embolectomies followed by redo ‐sternotomy, extensive annular debridement, root reconstruction with a modified Bentall technique, and hemiarch replacement. This case highlights the challenges in diagnosis and management of this rare disease entity and some of its devastating complications.
Background: Infective endocarditis (IE) is a serious illness with high morbidity and mortality. There is a need for early recognition of patients at risk of adverse events to guide management decisions and improve outcomes. Recent studies have identified inflammatory biomarkers including C-reactive protein (CRP), neutrophil-to-lymphocyte-ratio (NLR), and platelet-to-lymphocyte ratio (PLR) as prognostic factors in IE. We sought to identify simple laboratory parameters in IE patients as predictors of in-hospital mortality in our centre.
Background: Infective Endocarditis (IE) is a common pathology requiring admission to hospital. The length of stay in these patients can often be prolonged due to the need for prolonged courses of intravenous antibiotics. This can be associated with poor outcomes for the patient due to medical complications of prolonged hospital stay as well as increase the costs to the healthcare system. One way of reducing length of stay is utilising hospital in the home (HITH) services for administration of intravenous antibiotics in patients who are otherwise stable and can be discharged home safely, but still require completion of seve...
Background: Use of Echocardiography in suspected endocarditis is well established in SAB. On the contrary, GNB endocarditis is rare (1 –2%) but echocardiography requests are not uncommon suggesting a potential knowledge gap in its optimal utilisation for endocarditis.
Background: The ANZ population undergoing PPVI, including short to medium term outcomes, has not been fully characterised. In particular, there are concerns about infective endocarditis (IE) risk.
ConclusionIn this small series of Micra patients that developed SIEs post implant, the occurrence of bacteremia and/or endocarditis did not appear to lead to persistent bacteremia off antibiotics; most events resolved with antibiotic treatment.This article is protected by copyright. All rights reserved