The story of GARP: a potential target for cancer immunotherapy

(Medical University of South Carolina) In an article published in the March issue of Cancer Research, researchers at the Medical University of South Carolina reveal how the cell surface receptor GARP plays a role in T regulatory cell function and migration to the gut. Because the presence of T regulatory cells in the gut is generally associated with negative outcomes in patients with colorectal cancer, GARP could have potential as a therapeutic target for patients with this type of cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news