Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation

Flavokawain B (FKB) has been identified from kava root extracts as a potent apoptosis inducer for inhibiting the growth of various cancer cell lines, including prostate cancer. However, the molecular targets o...

Source: Cell Communication and Signaling - March 18, 2019 Category: Molecular Biology Authors: Xuesen Li, Victor Pham, Matthew Tippin, Dongjun Fu, Raymond Rendon, Liankun Song, Edward Uchio, Bang H. Hoang and Xiaolin Zi Tags: Research Source Type: research