Combined sarcoidosis and idiopathic pulmonary fibrosis (CSIPF): a novel disease phenotype?

we recently read with interest the case series on the novel disease entity of combined sarcoidosis and idiopathic pulmonary fibrosis (IPF/UIP) identified by Raghu et al. and defined as CSIPF (1). The association of these interstitial lung diseases (ILD) with different ethiopathogenesis and clinical course in a single patient is a real rare event, and the above description of 25 patients raises the question whether this association represents a mere coincidence or a novel phenotype consequent to a genetic undefined mutation.

Source: Respiratory Medicine - March 15, 2019 Category: Respiratory Medicine Authors: F. Bianchi, C. Piccioli, E. Rosi, L. Carobene, D. Spina, M.A. Mazzei, M. Bartolucci, C. Moroni, L. Novelli, P. Rottoli, E. Bargagli Tags: Correspondence Source Type: research