Comparison of the Full-Length and 152~528 Truncate of Human Cyclic Nucleotide Phosphodiesterase 4B2 for the Characterization of Inhibitors.

CONCLUSION: ST-hPDE4B2 with much higher activity yield may be a favorable alternative target to characterize/screen rolipram analogues as hPDE4B inhibitors in high-throughput mode. PMID: 30843483 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30843483?dopt=Abstract

Source: Combinatorial Chemistry and High Throughput Screening - March 5, 2019 Category: Chemistry Authors: Zhang X, He S, Hu X, Wu J, Li X, Lia F, Yang X Tags: Comb Chem High Throughput Screen Source Type: research

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