Diagnostic and interventional imaging techniques in breast cancer

Publication date: Available online 22 February 2019Source: Surgery (Oxford)Author(s): Simon Lowes, Alice Leaver, Alan RedmanAbstractImaging plays a critical role in the diagnosis and management of breast cancer. Two-view mammography and ultrasound form the mainstay of breast imaging and are essential components of the triple assessment. Digital mammography is rapidly replacing analogue mammography, and recent advances such as digital tomosynthesis add a third dimension to conventional 2D mammographic images. The versatility of ultrasound allows assessment of the breast and axilla as well as accurately targeted interventions, from the simple diagnostic core biopsy to preoperative tumour localization. It also guides large volume biopsies and excision of certain benign lesions, which in some cases can obviate surgical excision. Newer ultrasound techniques being applied to the breast and axilla include elastography and the use of intradermal microbubbles to guide the radiologist to the sentinel axillary node. Breast MRI is a powerful modality in assessing breast cancer. It can provide accurate information on size and multifocality of lesions, particularly those that are mammographically challenging such as lobular cancers, and it is also used to assess response to neoadjuvant chemotherapy and guide surgical management. CT scans, and in selected cases Positron Emission Tomography, play important roles in the assessment of metastatic disease.
Source: Surgery (Oxford) - Category: Surgery Source Type: research

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Source: Advances in Cancer Research - Category: Cancer & Oncology Authors: Tags: Adv Cancer Res Source Type: research
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Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
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Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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Source: Computational and Mathematical Methods in Medicine - Category: Statistics Tags: Comput Math Methods Med Source Type: research
Researchers from the Loma Linda University in California found drinking a third of a cup of milk every day, the equivalent of a small latte, spiked the risk by a third. Two cups saw it jump to nearly 80 per cent.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
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Source: JAMA: This Week's Audio Commentary - Category: General Medicine Authors: Source Type: podcasts
Publication date: Available online 25 February 2020Source: Life SciencesAuthor(s): Jing Chen, Na Li, Boxia Liu, Jun Ling, Wenjun Yang, Xiufeng Pang, Tao Li
Source: Life Sciences - Category: Biology Source Type: research
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Basel, 25 February 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has accepted the company’s Biologics License Application (BLA) for the fixed-dose combination (FDC) of Perjeta® (pertuzumab) and Herceptin® (trastuzumab) with hyaluronidase, administered by subc utaneous (SC) injection in combination with intravenous (IV) chemotherapy, for the treatment of eligible patients with HER2-positive breast cancer. The BLA for the FDC is based on results from the phase III FeDeriCa study, which demonstrated non-inferior levels of Perjeta in the blood (phar...
Source: Roche Investor Update - Category: Pharmaceuticals Source Type: news
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Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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