Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF

This mouse study demonstrates that repetitive inhalation of a single major house dust mite (HDM) allergen prevents HDM-induced allergic asthma development through suppressing the function of lung dendritic cells, thus providing an alternative to classical allergen-specific immunotherapy.

Source: Journal of Allergy and Clinical Immunology - February 20, 2019 Category: Allergy & Immunology Authors: Eline Haspeslagh, Manon Vanheerswynghels, Kim Deswarte, Justine van Moorleghem, Alain Jacquet, Bart N. Lambrecht, Hamida Hammad Source Type: research