LDK378 improves micro- and macro-circulation via alleviating STING-mediated inflammatory injury in a Sepsis rat model induced by Cecal ligation and puncture

Sepsis is a systemic inflammatory response syndrome caused by severe infections. LDK378, a second-generation ALK inhibitor, exhibits a potential anti-inflammatory function against sepsis. Micro- and macro-circ...

Source: Journal of Inflammation - February 18, 2019 Category: Allergy & Immunology Authors: Weiwei Ge, Qiaohua Hu, Xiangshao Fang, Juanhua Liu, Jing Xu, Juntao Hu, Xuefen Liu, Qin Ling, Yue Wang, He Li, Ming Gao, Longyuan Jiang, Zhengfei Yang and Wanchun Tang Tags: Research Source Type: research