A randomized double-blinded study to determine the effectiveness of utilizing intraperitoneal bupivacaine: Does it reduce post-operative opioid use following laparoscopic appendectomy?

DR. SAAD SHEBRAIN (Kalamazoo, Michigan): The finding of this study is that instillation of local anesthetic agents at the conclusion of laparoscopic appendectomy compared to placebo has a significant effect on reducing postoperative pain, opioid use and length of stay. The etiology of postoperative pain after laparoscopic surgery is complex and that could be partly explained by the induction of visceral trauma and inflammation and peritoneal irritation due to carbon dioxide pneumoperitoneum with stretching and parietal peritoneum.
Source: American Journal of Surgery - Category: Surgery Source Type: research