MIF inhibition enhances pulmonary angiogenesis and lung development in congenital diaphragmatic hernia.

CONCLUSION: Prenatal inhibition of MIF activity in CDH rat model improves angiogenesis and lung development. This selective intervention may be a future therapeutic strategy to reduce the morbidity and mortality of this devastating condition.
PMID: 30759452 [PubMed - as supplied by publisher]

Source: Pediatric Research - February 13, 2019 Category: Pediatrics Authors: Perveen S, Ayyasola K, Zagloul N, Patel H, Ochani K, Orner D, Benveniste H, Salerno M, Vaska P, Zuo Z, Alabed Y, Nasim M, Miller EJ, Ahmed M Tags: Pediatr Res Source Type: research