SHINE: No Improvement With Intense IV Glucose Control in Stroke SHINE: No Improvement With Intense IV Glucose Control in Stroke
Intense intravenous glucose control does not better improve functional outcomes after an ischemic stroke than standard subcutaneous insulin therapy — and may increase risk for hypoglycemia.Medscape Medical News
Kars C. J. Compagne, R. B. Goldhoorn, Maarten Uyttenboogaart, Robert J. van Oostenbrugge, Wim H. van Zwam, Pieter J. van Doormaal, Diederik W. J. Dippel, Aad van der Lugt, Bart J. Emmer, Adriaan C. G. M. van Es, the MR CLEAN investigators
Yanna Tong, Zhe Cheng, Gary B. Rajah, Honglian Duan, Lipeng Cai, Nan Zhang, Huishan Du, Xiaokun Geng, Yuchuan Ding
Authors: Blum A, Pastukh N, Sirchan R, Blum N, Chernikoff L, Vaispapir V Abstract BACKGROUND: Endothelial progenitor cells may have a role in ongoing endothelial repair. Impaired mobilization or depletion of these cells may contribute to progression of vascular disease. Our hypothesis was that endothelial progenitor cells would be suppressed in patients with acute cerebrovascular event based on our previous study that found severe endothelial dysfunction in those patients. OBJECTIVES: To study the ability of patients with acute stroke to build colonies of endothelial progenitor cells. METHODS: We studied th...
This report explains the potential interaction between warfarin and astaxanthin in a 69-year-old Thai woman with history of ischemic stroke. Before taking astaxanthin, the patient used constant doses of warfarin, atenolol, digoxin, aspirin, omeprazole, and simvastatin concomitantly for 17 days without any signs and symptoms of adverse events. One day after astaxanthin was supplemented to her treatment regimen, ecchymosis was found on the right side of her groin and thigh. On the next day, area of ecchymosis was larger. International normalized ratio (INR) values increased from 1.4 to 10.38. Warfarin and astaxanthin were wi...
Introduction: Galen vein aneurysm is the most common congenital arteriovenous (AV) malformation. It consists of an arteriovenous shunt dilating vascular bed. Brain structures of the posterior cranial fossa are often compressed by this dilatation. The most often manifestations are ischemic changes of neonatal brain as a stroke, steal phenomenon, hydrocephalus or heart failure.
Introduction: Venous stroke (VS) is a rare form of acute ischemic stroke as a thrombosis of Trolard vein (the frequency 0.1% to 3 –5%) occurs when the outflow of blood from the superficial cortical veins of the brain along the large anastomotic vein of Trolard and the small anastomotic vein of Labbe in turn, flow into the large vein of Gallen, which collects blood from the deep cerebral veins and falls into a straight sinus. Verification of VS is difficult due to the following features: the defeat of the parieto-occipital region gives meagre focal neurologic symptoms and more pronounced cerebral symptoms.
We present a rare case of severe intractable menorrhagia occurring with the first period in a 12-year-old girl who has a positive family history of bleeding disorder. She presented with a series of challenges in terms of diagnosis, management, and therapy.
Muhammad Munir, Jake Ursenbach, Meaghan Reid, Rani Gupta Sah, Meng Wang, Amith Sitaram, Arooj Aftab, Sana Tariq, Giovanna Zamboni, Ludovica Griffanti, Eric E. Smith, Richard Frayne, Tolulope T. Sajobi, Shelagh B. Coutts, Christopher D. d'Esterre, Philip A. Barber, Alzheimer's Disease Neuroimaging Initiative
Objective: To evaluate the predictive value of epicardial fat thickness (EFT) in CHA2DS2-VASc (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, previous stroke or transient ischemic attack, vascular disease, age 65-74 years, sex category) score risk groups.Methods: A total of 158 consecutive patients (75 females, 83 males, mean age 70.8 ±6.3 years) admitted routinely for cardiologic control were divided into two groups according to their CHA2DS2-VASc scores (scores 0 and 1 were regarded as low risk, and score ≥2 as high risk). One hun...
Condition: Acute Ischemic Stroke Intervention: Drug: Eptifibatide Injection Sponsor: Ministry of Science and Technology of the People´s Republic of China Not yet recruiting