Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling

Uraemic syndrome of chronic kidney disease: altered remote sensing and signallingUraemic syndrome of chronic kidney disease: altered remote sensing and signalling, Published online: 06 February 2019; doi:10.1038/s41581-019-0111-1The plasma accumulation of uraemic solutes seen in chronic kidney disease is associated with dysregulated homeostasis. In this Review, Nigam and Bush discuss uraemic syndrome in the context of the remote sensing and signalling hypothesis, which describes small-molecule-mediated communication between tissues and organs.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research