Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican population

Heterozygous germline TP53 gene mutations result in Li-Fraumeni Syndrome (LFS). Breast cancer (BC) is the most frequent tumor in young women with LFS. An important issue related to BC in the Mexican population is...

https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5312-2

Source: BMC Cancer - February 1, 2019 Category: Cancer & Oncology Authors: Lenny N. Gallardo-Alvarado, Mar ía Teresa Tusié-Luna, María Isabel Tussié-Luna, José Díaz-Chávez, Yayoi X. Segura, Enrique Bargallo-Rocha, Cynthia Villarreal, Luis A. Herrera-Montalvo, Enrique M. Herrera-Medina and David F. Cantu-de Leon Tags: Research article Source Type: research