Obesity, climate change and hunger must be fought as one, health experts declare

Maybe, when it comes to finding a way out of a global crisis of obesity, we ’re just thinking too small.Maybe the steps needed to reverse a pandemic of unhealthy weight gain are the same as those needed to solve two other crises of human health: malnutrition and climate change.So instead of trying...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news

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ConclusionThe present SR provides state-of-the-art information about the use of metabolomics as an approach to understanding the dynamics of metabolic processes involved in human obesity and emphasizes metabolic signatures related to obesity phenotypes.
Source: Metabolomics - Category: Biology Source Type: research
AbstractPurpose of ReviewIn this review, we focus on microbiota modulation using non-digestible carbohydrate and polyphenols (i.e., prebiotics) that have the potential to modulate body weight.Recent FindingsPrebiotics derived from plants have gained the interest of public and scientific communities as they may prevent diseases and help maintain health.SummaryMaintaining a healthy body weight is key to reducing the risk of developing chronic metabolic complications. However, the prevalence of obesity has increased to pandemic proportions and is now ranked globally in the top five risk factors for death. While diet and behav...
Source: Current Nutrition Reports - Category: Nutrition Source Type: research
Diabetes has reached pandemic magnitude globally. Over the last 20 years, there has been increasing evidence that bariatric surgery can elicit potent effects to improve the metabolic state in obese subjects with T2D. However, bariatric surgery is associated with a background rate of severe adverse events that renders this intervention unappealing for many patients. Approximately, 4% severe adverse events and up to 3% mortality rate have been reported. Therefore, novel minimally invasive procedures are under development that can elicit some of the benefits of bariatric surgery but with a more favorable safety and tolerability profile.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Sunday abstract Source Type: research
Obesity is a worldwide pandemic and bariatric surgery is the most effective treatment modality. Despite its satisfactory clinical results, some patients regain part of their lost weight. Traditionally, revisional surgery to reduce the gastrojejunal anastomosis (GJA) is offered to these patients. However, revisional procedures carry a higher complication rate than primary bariatric surgeries including fistulas and dehiscence with incidences ranging from 1 to 8.3% after laparoscopic RYGB. The diagnosis and treatment of bariatric surgery leaks are challenging due to nonspecific clinical and laboratory findings.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Oral abstract Source Type: research
The global pandemic of obesity has a gigantic social and financial impact, and alternatives for the treatment and control of this pathology are imperative. Morbid obese Patients are treated very efficiently by the various Bariatric surgery techniques, while overweight patients have good results with drug interventions and changes in lifestyle. For the patients who are at the intersection of these two strategies, the endoscopic treatment of obesity with the intragastric balloon is a very interesting and widely used alternative.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Saturday abstract Source Type: research
Obesity has become a global pandemic, and the complex physical, social, and psychological dimensions of the disease affect all ages and socioeconomic groups. Endoscopic sleeve gastroplasty (ESG) is a minimally invasive endoscopic bariatric therapy with demonstrated efficacy and durability for weight loss and obesity-related comorbidities and is in many cases an alternative to laparoscopic or open surgical approaches.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Saturday abstract Source Type: research
When primitive vertebrates evolved from ancestral members of the animal kingdom and acquired complex locomotive and neurological toolsets, a constant supply of energy became necessary for their continued survival. To help fulfill this need, the endocannabinoid (eCB) system transformed drastically with the addition of the cannabinoid-1 receptor (CB1R) to its gene repertoire. This established an eCB/CB1R signaling mechanism responsible for governing the whole organism’s energy balance, with its activation triggering a shift towards energy intake and storage in the brain and the peripheral organs (i.e. liver and adipose...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
This study has relevance for other Pacific Island nations and all nations concerned with addressing obesity and other diet-related NCDs.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Abstract Obesity is a pandemic disease affecting around 15% of the global population. Obesity is a major risk factor for other conditions, such as type 2 diabetes and cardiovascular diseases. The adipose tissue is the main secretor of leptin, an adipokine responsible for the regulation of food intake and energy expenditure. Obese individuals become hyperleptinemic due to increased adipogenesis. Leptin acts through the leptin receptor and induces several immunometabolic changes in different cell types, including adipocytes and Mϕs. Adipose tissue resident Mϕs (ATMs) are the largest leukocyte population in the adi...
Source: Journal of Leukocyte Biology - Category: Hematology Authors: Tags: J Leukoc Biol Source Type: research
With the rising prevalence of obesity has come an increasing awareness of its impact on communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic, obesity was identified for the first time as a risk factor for increased disease severity and mortality in infected individuals. Over-nutrition that results in obesity causes a chronic state of meta-inflammation with systemic implications for immunity. Obese hosts exhibit delayed and blunted antiviral responses to influenza virus infection, and they experience poor recovery from the disease. Furthermore, the efficacy of antivirals and vaccines is reduced...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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