Complexation of luteolin with lead (II): Spectroscopy characterization and theoretical researches.

Complexation of luteolin with lead (II): Spectroscopy characterization and theoretical researches. J Inorg Biochem. 2019 Jan 15;193:25-30 Authors: Wang Q, Zhao L, Zhao H, Liu X, Gao L, Cheng N, Cao W Abstract The interactions of (CH3COO)2Pb·3H2O (lead acetate trihydrate) with luteolin, 5,7,3',4'-tetrahydroxyflavone, were investigated in methanol solution. The spectroscopy (UV-Vis, FT-IR, HPLC-MS, 1H NMR) and elemental analysis were adopted to assess the interaction of luteolin and Pb(II). The results show that luteolin reacts with Pb(II) through the chelating sites of 4‑carbonyl and 5-hydroxy in two luteolin molecules. The structures, energies, CDA (charge decomposition analysis) and orbitals analysis of the ligand and complex have been analyzed according to quantum-chemical calculation, which is further proofed that luteolin molecule can effectively chelate Pb(II) by 5-hydroxyl-4-oxo chelating site. It is speculated that luteolin has a high potential of becoming a health care product to eliminate lead cation in the future. PMID: 30669063 [PubMed - as supplied by publisher]
Source: Journal of Inorganic Biochemistry - Category: Biochemistry Authors: Tags: J Inorg Biochem Source Type: research