Serum α-1 acid glycoprotein 1 is a biomarker for the prediction of targeted therapy resistance in advanced EGFR-positive lung adenocarcinoma.

CONCLUSIONS: Serum ORM1 has an important diagnostic value for the diagnosis of EGFR-positive LUAD and EGFR-TKI resistance in patients especially with advanced EGFR-positive LUAD. Our findings suggest that serum ORM1 is a biomarker in the prediction of EGFR-TKI resistance in EGFR-positive LUAD.
PMID: 30663564 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - January 19, 2019 Category: Chemistry Authors: Xu YF, Xu Y, Li X, Yang XM Tags: Comb Chem High Throughput Screen Source Type: research