Abstract #136: Translational Neuromodulation of Motor-Output Using Trans-spinal Direct Current Stimulation (tsDCS) in a Large Animal Model

Introduction: A mounting approach for rewiring and strengthening the corticospinal system (CS) following a spinal injury is to augment activity-dependent mechanisms that promote adaptive plasticity in the spinal cord. Emerging therapies from our lab use patterned electrical stimulation of motor cortex (M1) alone and in combination with cervical trans-spinal direct current stimulation (tsDCS) in the rat to promote corticospinal axon outgrowth, to strengthen CS connections, and to restore skilled motor function.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Preston Williams, John Brandenburg, Dennis Q. Truong, Alan C. Seifert, Adrish Sarkar, Junqian Xu, Marom Bikson, John Martin Source Type: research